SNAP-7941

SNAP-7941 is a drug used in scientific research, which is a selective, non-peptide antagonist at the melanin concentrating hormone receptor MCH₁. In initial animal studies it had promising anxiolytic, antidepressant and anorectic effects,^[1][2] but subsequent trial results were disappointing,^[3] and the main significance of SNAP-7941 is as the lead compound from which more potent and selective antagonists such as SNAP-94847 were developed,^[4][5] although it continues to be used for research into the function of the MCH₁ receptor.^[6][7]

SNAP-7941

Identifiers
CAS Number	387825-78-7 N[EPA]
PubChem CID	11520239
ChemSpider	9695027
ChEMBL	ChEMBL185271 N
CompTox Dashboard (EPA)	DTXSID101028551
Chemical and physical data
Formula	C33H41F2N5O6
Molar mass	641.717 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(C)C(=O)Nc(c4)cccc4C3CCN(CC3)CCCNC(=O)N(C(=O)NC=1COC)C(C=1C(=O)OC)c(cc2F)ccc2F
InChI InChI=1S/C31H37F2N5O6/c1-19(39)35-23-7-4-6-21(16-23)20-10-14-37(15-11-20)13-5-12-34-30(41)38-28(22-8-9-24(32)25(33)17-22)27(29(40)44-3)26(18-43-2)36-31(38)42/h4,6-9,16-17,20,28H,5,10-15,18H2,1-3H3,(H,34,41)(H,35,39)(H,36,42)/t28-/m0/s1 Key:FWMHZWMPUWAUPL-NDEPHWFRSA-N
NY (what is this?)  (verify)