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SP-624
Sirtuin-6 activator From Wikipedia, the free encyclopedia
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SP-624 is a sirtuin-6 (SIRT6) activator which is under development for the treatment of major depressive disorder and schizophrenia.[1][2][3][4] It is taken by mouth.[1] As of August 2024, SP-624 is in phase 2 clinical trials for major depressive disorder and is in phase 1/2 clinical trials for schizophrenia.[1][2][3] It is under development by Sirtsei Pharmaceuticals and Arrivo BioVentures.[1][2][4] The drug is said to be a small molecule, but its chemical structure does not yet seem to have been disclosed.[1][2]
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