SPRY3

Protein sprouty homolog 3 is a protein that in humans is encoded by the SPRY3 gene.^[3][4]

SPRY3
Identifiers
Aliases	SPRY3, Hspry-3, Gm1409, Gm391, sprouty3, Spry3, sprouty RTK signaling antagonist 3
External IDs	OMIM: 300531; MGI: 1345188; HomoloGene: 4265; GeneCards: SPRY3; OMA:SPRY3 - orthologs
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence bone marrow cells prefrontal cortex gastrocnemius muscle stromal cell of endometrium left adrenal gland smooth muscle tissue deltoid muscle monocyte ascending aorta n/a More reference expression data BioGPS n/a
Gene ontology Molecular function molecular function Cellular component cytoplasm membrane cytosol Biological process regulation of signal transduction axon development multicellular organism development negative regulation of fibroblast growth factor receptor signaling pathway negative regulation of MAP kinase activity negative regulation of Ras protein signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10251 236576 Ensembl n/a ENSMUSG00000061654 UniProt O43610 Q3UUD2 RefSeq (mRNA) NM_001304990 NM_005840 NM_001394353 NM_001394354 NM_001394355 NM_001030293 RefSeq (protein) NP_001291919 NP_005831 NP_001025464 NP_001388778 NP_001388779 NP_001388780 Location (UCSC) n/a n/a PubMed search [1] [2]
Wikidata
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The SPRY3 gene is one of the genes found in the pseudoautosomal regions of the human sex chromosomes (i.e. those 19 genes that are found on both the X and Y chromosome). It is located in the PAR2 region.