SCO-spondin

SCO-spondin is a protein that in humans is encoded by the SSPO gene.^[5][6][7] SCO-spondin is secreted by the subcommissural organ, and contributes to commissural axon growth and the formation of Reissner's fiber, a fibrous aggregation of secreted molecules extending from the subcommissural organ to the end of the spinal cord.^[8]

SSPOP
Identifiers
Aliases	SSPOP, SCO-spondin, SCO-spondin, pseudogene, SSPO
External IDs	OMIM: 617356; MGI: 2674311; HomoloGene: 45453; GeneCards: SSPOP; OMA:SSPOP - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q36.1 Start 149,776,042 bp[1] End 149,833,979 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 B2.3 Start 48,425,163 bp[2] End 48,478,184 bp[2]
Gene ontology Molecular function peptidase inhibitor activity Cellular component extracellular region extracellular space Biological process negative regulation of peptidase activity cell adhesion nervous system development cell differentiation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23145 243369 Ensembl ENSG00000197558 ENSMUSG00000029797 UniProt A2VEC9 Q8CG65 RefSeq (mRNA) NM_198455 NM_173428 RefSeq (protein) NP_940857 NP_775604 Location (UCSC) Chr 7: 149.78 – 149.83 Mb Chr 6: 48.43 – 48.48 Mb PubMed search [3] [4]
Wikidata
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