Syntaxin binding protein 2

Syntaxin-binding protein 2 is a protein that in humans is encoded by the STXBP2 gene.^[5][6]

STXBP2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4CCA
Identifiers
Aliases	STXBP2, FHL5, Hunc18b, MUNC18-2, UNC18-2, UNC18B, pp10122, Syntaxin binding protein 2
External IDs	OMIM: 601717; MGI: 107370; HomoloGene: 55530; GeneCards: STXBP2; OMA:STXBP2 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.2 Start 7,636,881 bp[1] End 7,647,873 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8 A1.1|8 1.92 cM Start 3,680,955 bp[2] End 3,693,644 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte monocyte mucosa of transverse colon body of pancreas upper lobe of left lung right lung right uterine tube left testis right lobe of thyroid gland right testis Top expressed in granulocyte neural layer of retina yolk sac superior frontal gyrus lip right kidney submandibular gland saccule duodenum stomach More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding syntaxin-1 binding syntaxin-3 binding Cellular component cytolytic granule tertiary granule SNARE complex azurophil granule specific granule apical plasma membrane extracellular exosome plasma membrane zymogen granule membrane extracellular region cytosol phagocytic vesicle Biological process protein transport neutrophil degranulation vesicle docking involved in exocytosis regulation of mast cell degranulation leukocyte mediated cytotoxicity vesicle-mediated transport exocytosis platelet degranulation transport cellular response to interferon-gamma Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6813 20911 Ensembl ENSG00000076944 ENSMUSG00000004626 UniProt Q15833 Q64324 RefSeq (mRNA) NM_001127396 NM_001272034 NM_006949 NM_011503 NM_001357168 RefSeq (protein) NP_001120868 NP_001258963 NP_008880 NP_035633 NP_001344097 Location (UCSC) Chr 19: 7.64 – 7.65 Mb Chr 8: 3.68 – 3.69 Mb PubMed search [3] [4]
Wikidata
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