Secnidazole

Secnidazole (trade names Flagentyl, Sindose, Secnil, Solosec) is a nitroimidazole anti-infective used to treat bacterial vaginosis and trichomoniasis.^[2][1] It is taken orally.^[1]

Secnidazole

Clinical data
Trade names	Solosec
Other names	PM-185184; RP-14539; SYM-1219
AHFS/Drugs.com	International Drug Names
License data	US DailyMed: Secnidazole
Routes of administration	Oral[1]
ATC code	P01AB07 (WHO)
Legal status
Legal status	US: ℞-only
Identifiers
IUPAC name 1-(2-Methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol
CAS Number	3366-95-8 N
PubChem CID	71815
ChemSpider	64839 Y
UNII	R3459K699K
KEGG	D07353 Y
ChEBI	CHEBI:140628
ChEMBL	ChEMBL498847 Y
CompTox Dashboard (EPA)	DTXSID3045934
ECHA InfoCard	100.020.123
Chemical and physical data
Formula	C7H11N3O3
Molar mass	185.183 g·mol−1
3D model (JSmol)	Interactive image
SMILES [O-] [N+](=O)c1cnc(n1CC(O)C)C
InChI InChI=1S/C7H11N3O3/c1-5(11)4-9-6(2)8-3-7(9)10(12)13/h3,5,11H,4H2,1-2H3 Y Key:KPQZUUQMTUIKBP-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Structurally it actually methyl-metronidazole. Effectiveness in the treatment of dientamoebiasis has been reported.^[3] It has also been tested against Atopobium vaginae.^[4]

In the United States, secnidazole is FDA-approved for the treatment of bacterial vaginosis and trichomoniasis in adult women.^[2][5] It was approved in the United States in 2017.^[1]