Simmerafil

Simmerafil^[1] (TPN171H) is a selective PDE5 inhibitor^[2] in development for the treatment of erectile dysfunction^[3] and pulmonary hypertension.^[4]

Simmerafil

Clinical data
Other names	TPN171
Legal status
Legal status	Investigational
Identifiers
IUPAC name N-[3-(4,5-Diethyl-6-oxo-1H-pyrimidin-2-yl)-4-propoxyphenyl]-2-(4-methylpiperazin-1-yl)acetamide
CAS Number	1229018-87-4
PubChem CID	136197286
Chemical and physical data
Formula	C24H35N5O3
Molar mass	441.576 g·mol−1