Site-specific DNA-methyltransferase (cytosine-N4-specific)

Site-specific DNA-methyltransferase (cytosine-N4-specific) (EC 2.1.1.113, modification methylase, restriction-modification system, DNA[cytosine-N4]methyltransferase, m4C-forming MTase, S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:DNA-cytosine N4-methyltransferase.^[1][2][3][4] This enzyme catalyses the following chemical reaction:

S-adenosyl-L-methionine + DNA cytosine ${\displaystyle \rightleftharpoons }$ S-adenosyl-L-homocysteine + DNA N4-methylcytosine

Site-specific DNA-methyltransferase (cytosine-N4-specific)
Identifiers
EC no.	2.1.1.113
CAS no.	169592-50-1
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This is a large group of enzymes.^[5]

See also

• DNA methyltransferase