Small nucleolar RNA SNORD24

In molecular biology, U24 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs.^[1] C/D box snoRNAs have been shown to act as methylation guides for a number of RNA targets.^[2][3] U24 is encoded within an intron of the gene for ribosomal protein L7a in mammals, chicken and Fugu.^[4] The U76/SNORD76 snoRNA is found in an intron of the uRNA host gene (UHG) growth arrest specific 5 (GAS5) transcript gene.^[5] snoRNAs Z20 and U76 snoRNAs show clear similarity to U24.

Small nucleolar RNA SNORD24
Predicted secondary structure and sequence conservation of SNORD24
Identifiers
Symbol	SNORD24
Alt. Symbols	U24
Rfam	RF00069
Other data
RNA type	Gene; snRNA; snoRNA; C/D-box
Domain(s)	Eukaryota
GO	GO:0006396 GO:0005730
SO	SO:0000593
PDB structures	PDBe

An experiment that looked at 22 different non-small-cell lung cancer tissues found that SNORD33, SNORD66 and SNORD76 were over-expressed relative to matched noncancerous lung tissues.^[6]