Spheroidene monooxygenase

Spheroidene monooxygenase (EC 1.14.15.9, CrtA, acyclic carotenoid 2-ketolase, spirilloxantin monooxygenase, 2-oxo-spirilloxanthin monooxygenase) is an enzyme with systematic name spheroidene, reduced-ferredoxin:oxygen oxidoreductase (spheroiden-2-one-forming).^[1][2] This enzyme catalyses the following chemical reaction

spheroidene + reduced ferredoxin + O₂ ${\displaystyle \rightleftharpoons }$ spheroiden-2-one + oxidized ferredoxin + H₂O

spirilloxantin + reduced ferredoxin + O₂ ${\displaystyle \rightleftharpoons }$ 2-oxospirilloxanthin + oxidized ferredoxin + H₂O

2'-oxospirilloxanthin + reduced ferredoxin + O₂ ${\displaystyle \rightleftharpoons }$ 2,2'-dioxospirilloxanthin + oxidized ferredoxin + H₂O

Spheroidene monooxygenase
Identifiers
EC no.	1.14.15.9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

The enzyme is involved in spheroidenone biosynthesis and in 2,2'-dioxospirilloxanthin biosynthesis.