SrbA sRNA

SrbA (sRNA regulator of biofilms A) is a small regulatory non-coding RNA identified in pathogenic Pseudomonas aeruginosa^[1]. It is important for biofilm formation and pathogenicity. Bacterial strain with deleted SrbA had reduced biofilm mass. As the ability to form biofilms ^[2] can contribute to the ability a pathogen to thrive within the host, the C. elegans hosts infected with the srbA deleted strain displayed significantly lower mortality rate than the wild-type strain. However, the deletion of srbA had no effect on growth or antibiotic resistance in P. aeruginosa.^[3]

See also

• NrsZ small RNA
• Pseudomonas sRNA
• AsponA antisense RNA