Statine

Statine
Names
	IUPAC name (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid
Identifiers
CAS Number	49642-07-1 ;
3D model (JSmol)	Interactive image;
Abbreviations	AHMHA, Sta
ChEBI	CHEBI:45769;
ChemSpider	110446;
ECHA InfoCard	100.161.428
PubChem CID	123915;
UNII	YTC77XR1EK ;
CompTox Dashboard (EPA)	DTXSID00964315 ;
	InChI InChI=1S/C8H17NO3/c1-5(2)3-6(9)7(10)4-8(11)12/h5-7,10H,3-4,9H2,1-2H3,(H,11,12)/t6-,7-/m0/s1 Key: DFVFTMTWCUHJBL-BQBZGAKWSA-N;
	SMILES N[C@@H](CC(C)C)[C@@H](O)CC(O)=O;
Properties
Chemical formula	C8H17NO3
Molar mass	175.228 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Statine is a gamma amino acid that occurs twice in the sequence of pepstatin, a protease inhibitor that is active against pepsin and other acid proteases.^[1] It is thought to be responsible for the inhibitory activity of pepstatin because it mimics the tetrahedral transition state of peptide catalysis.^[2]

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References