SucA RNA motif

The sucA RNA motif is a conserved RNA structure found in bacteria of the order Burkholderiales.^[1] RNAs within this motif are always found in the presumed 5' UTR of sucA genes. sucA encodes a subunit of an enzyme that participates in the citric acid cycle by synthesizing succinyl-CoA from 2-oxoglutarate. A part of the conserved structure overlaps predicted Shine-Dalgarno sequences (involved in ribosome binding) of the downstream sucA genes. Because of the RNA motif's consistent gene association and a possible mechanism for sequestering the ribosome binding site, it was proposed that the sucA RNA motif corresponds to a cis-regulatory element. Its relatively complex secondary structure could indicate that it is a riboswitch. However, the function of this RNA motif remains unknown.

SucA RNA motif
Predicted secondary structure and sequence conservation of sucA
Identifiers
Symbol	sucA
Rfam	RF01070
Other data
RNA type	Cis-reg
Domain	Bacteria
SO	SO:0005836
PDB structures	PDBe

See also

• SucA-II RNA motif
• SucC RNA motif