Succinate-semialdehyde dehydrogenase (NADP+)

Succinate-semialdehyde dehydrogenase (NADP⁺) (EC 1.2.1.79, succinic semialdehyde dehydrogenase (NADP⁺), succinyl semialdehyde dehydrogenase (NADP⁺), succinate semialdehyde:NADP⁺ oxidoreductase, NADP-dependent succinate-semialdehyde dehydrogenase, GabD) is an enzyme with systematic name succinate-semialdehyde:NADP⁺ oxidoreductase.^[1][2] This enzyme catalyses the following chemical reaction

succinate semialdehyde + NADP⁺ + H2O ${\displaystyle \rightleftharpoons }$ succinate + NADPH + 2 H⁺

Succinate-semialdehyde dehydrogenase (NADP+)
Identifiers
EC no.	1.2.1.79
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
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This enzyme participates in the degradation of glutamate and 4-aminobutyrate.