Sucrose synthase

In enzymology, a sucrose synthase (EC 2.4.1.13) is an enzyme that catalyzes the chemical reaction

NDP-glucose + D-fructose ⇌ NDP + sucrose

Ribbon diagram of sucrose synthase-1 3S27 structure, isolated from Arabidopsis thaliana.^[1]

sucrose synthase
Identifiers
EC no.	2.4.1.13
CAS no.	9030-05-1
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Sucrose synthase
Identifiers
Symbol	Sucrose_synth
Pfam	PF00862
InterPro	IPR000368
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

Thus, the two substrates of this enzyme are NDP-glucose and D-fructose, whereas its two products are NDP and sucrose.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase. Other names in common use include UDPglucose-fructose glucosyltransferase, sucrose synthetase, sucrose-UDP glucosyltransferase, sucrose-uridine diphosphate glucosyltransferase, and uridine diphosphoglucose-fructose glucosyltransferase. This enzyme participates in starch and sucrose metabolism.