Sulfaguanidine

Sulfaguanidine is a sulfonamide.

Sulfaguanidine

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	A07AB03 (WHO)
Identifiers
IUPAC name 4-Amino-N-[amino(imino)methyl]benzenesulfonamide
CAS Number	57-67-0
PubChem CID	5324
ChemSpider	5133
UNII	15XQ8043FN
KEGG	D02437 Y
CompTox Dashboard (EPA)	DTXSID1023609
ECHA InfoCard	100.000.314
Chemical and physical data
Formula	C7H10N4O2S
Molar mass	214.24 g·mol−1
3D model (JSmol)	Interactive image
Melting point	190 to 193 °C (374 to 379 °F)
SMILES c1cc(N)ccc1S(=O)(=O)N=C(N)N
InChI InChI=1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11) Key:BRBKOPJOKNSWSG-UHFFFAOYSA-N
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Sulfaguanidine is a guanidine derivative of sulfanilamide used in veterinary medicine. Sulfaguanidine is poorly absorbed from the gut which makes it suitable for the treatment of bacillary dysentery and other enteric infections.^[1]

Sulphaguanidine (II) was independently prepared by Marshall, Bratton, White, and Litchfield and Roblin, Williams, Winnek, and English in 1940, and introduced for the treatment of bacillary dysentery on the basis of its poor absorption from the gut. Its orally administered route of administration is now well established.^[2]