Super Conserved Receptor Expressed in Brain

For the American educational organization, see Southern Regional Education Board.

The Super Conserved Receptor Expressed in Brain (SREB) family are a group of related G-protein coupled receptors.^[1] Since no endogenous ligands have yet been identified for these receptors, they are classified as orphan receptors. Receptors within the group include SREB1 (GPR27), SREB2 (GPR85), and SREB3 (GPR173).^[2]

G protein-coupled receptor 27
Identifiers
Symbol	GPR27
Alt. symbols	SREB1
NCBI gene	2850
HGNC	4482
OMIM	605187
RefSeq	NM_018971
UniProt	Q9NS67
Other data
Locus	Chr. 3 p21-p14
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G protein-coupled receptor 85
Identifiers
Symbol	GPR85
Alt. symbols	SREB2
NCBI gene	54329
HGNC	4536
OMIM	605188
RefSeq	NM_018970
UniProt	P60893
Other data
Locus	Chr. 7 q31
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G protein-coupled receptor 173
Identifiers
Symbol	GPR173
Alt. symbols	SREB3
NCBI gene	54328
HGNC	18186
OMIM	300253
RefSeq	NM_018969
UniProt	Q9NS66
Other data
Locus	Chr. X p11
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