Suritozole

Suritozole
Clinical data
ATC code	none;
Identifiers
	IUPAC name 5-(3-fluorophenyl)-2,4-dimethyl-2,4-dihydro-3H-1,2,4-triazole-3-thione;
CAS Number	110623-33-1 ;
PubChem CID	25431;
ChemSpider	23743 ;
UNII	3H7H68317X;
KEGG	D05980 ;
CompTox Dashboard (EPA)	DTXSID10149333 ;
Chemical and physical data
Formula	C10H10FN3S
Molar mass	223.27 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Cn1c(=S)n(C)nc1-c2cccc(F)c2;
	InChI InChI=1S/C10H10FN3S/c1-13-9(12-14(2)10(13)15)7-4-3-5-8(11)6-7/h3-6H,1-2H3 ; Key:IWDUZEHNLHFBRZ-UHFFFAOYSA-N ;
	(what is this?) (verify)

Suritozole (MDL 26,479) is an investigational cognition enhancer. It acts as a partial inverse agonist at the benzodiazepine receptor site on the GABA_A ion channel complex, but does not have either anxiogenic or convulsant effects, unlike other BZD inverse agonists such as DMCM.^[1] It was investigated for the treatment of depression and Alzheimer's disease in the 90s,^[2] but clinical development seems to have been discontinued.

Quick Facts Clinical data, ATC code ...

Synthesis