NDC1

Nucleoporin NDC1 is a protein that in humans is encoded by the TMEM48 gene.^[5][6][7] It anchors aladin to the nuclear pore complex.^[8]

NDC1
Identifiers
Aliases	NDC1, NET3, TMEM48, NDC1 transmembrane nucleoporin
External IDs	OMIM: 610115; MGI: 1920037; HomoloGene: 41224; GeneCards: NDC1; OMA:NDC1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p32.3 Start 53,765,478 bp[1] End 53,838,463 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 C7 Start 107,224,981 bp[2] End 107,273,543 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte gonad ventricular zone tibia gingival epithelium epithelium of nasopharynx mucosa of colon mucosa of sigmoid colon germinal epithelium testicle Top expressed in tail of embryo genital tubercle primitive streak cumulus cell spermatocyte epiblast maxillary prominence condyle yolk sac medullary collecting duct More reference expression data BioGPS More reference expression data
Gene ontology Molecular function structural constituent of nuclear pore Cellular component cytoplasm integral component of membrane nuclear membrane nuclear envelope membrane plasma membrane nuclear pore actin cytoskeleton nucleus spindle pole body nuclear pore transmembrane ring host cell Biological process mRNA transport nuclear pore complex assembly viral transcription protein sumoylation mitotic nuclear membrane disassembly homologous chromosome pairing at meiosis spermatogenesis protein transport regulation of cellular response to heat viral process mRNA export from nucleus intracellular transport of virus tRNA export from nucleus spindle pole body duplication regulation of gene silencing by miRNA regulation of glycolytic process transport nuclear pore organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55706 72787 Ensembl ENSG00000058804 ENSMUSG00000028614 UniProt Q9BTX1 Q8VCB1 RefSeq (mRNA) NM_001168551 NM_018087 NM_028355 RefSeq (protein) NP_001162023 NP_060557 NP_082631 Location (UCSC) Chr 1: 53.77 – 53.84 Mb Chr 4: 107.22 – 107.27 Mb PubMed search [3] [4]
Wikidata
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