Tropomodulin 1

Tropomodulin-1 is a protein that in humans is encoded by the TMOD1 gene.^[4][5][6]

TMOD1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4PKG, 4PKH, 4PKI, 4Z8G, 4Z94
Identifiers
Aliases	TMOD1, D9S57E, ETMOD, TMOD, tropomodulin 1
External IDs	OMIM: 190930; MGI: 98775; HomoloGene: 20701; GeneCards: TMOD1; OMA:TMOD1 - orthologs
Gene location (Mouse) Chr. Chromosome 4 (mouse)[1] Band 4 B1|4 24.49 cM Start 46,038,935 bp[1] End 46,116,032 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastrocnemius muscle gastric mucosa spinal ganglia left ventricle skeletal muscle tissue body of tongue quadriceps femoris muscle vastus lateralis muscle deltoid muscle trigeminal ganglion Top expressed in quadriceps femoris muscle right ventricle muscle of thigh myocardium of ventricle gastrocnemius muscle temporal muscle utricle skeletal muscle tissue medial head of gastrocnemius muscle sternocleidomastoid muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function actin filament binding actin binding tropomyosin binding Cellular component membrane COP9 signalosome cytoskeleton cytosol cortical cytoskeleton cytoplasm sarcomere myofibril actin filament striated muscle thin filament Biological process adult locomotory behavior lens fiber cell development muscle filament sliding pointed-end actin filament capping muscle contraction actin filament organization myofibril assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7111 21916 Ensembl n/a ENSMUSG00000028328 UniProt P28289 P49813 RefSeq (mRNA) NM_003275 NM_001166116 NM_021883 RefSeq (protein) NP_001159588 NP_003266 NP_068683 Location (UCSC) n/a Chr 4: 46.04 – 46.12 Mb PubMed search [2] [3]
Wikidata
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