Trafficking protein particle complex 11

Trafficking protein particle complex 11 is a protein that in humans is encoded by the TRAPPC11 gene. ^[5]

TRAPPC11
Identifiers
Aliases	TRAPPC11, C4orf41, FOIGR, GRY, LGMD2S, trafficking protein particle complex 11, LGMDR18, trafficking protein particle complex subunit 11
External IDs	OMIM: 614138; MGI: 2444585; HomoloGene: 11076; GeneCards: TRAPPC11; OMA:TRAPPC11 - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q35.1 Start 183,659,267 bp[1] End 183,713,594 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 B1.1 Start 47,943,150 bp[2] End 47,986,505 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon gonad monocyte ventricular zone right adrenal cortex cerebellar hemisphere right ovary left ovary right hemisphere of cerebellum tonsil Top expressed in hand otic vesicle otolith organ utricle arcuate nucleus superior cervical ganglion parotid gland ventromedial nucleus median eminence Gonadal ridge More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component cytosol Golgi apparatus TRAPP complex Biological process vesicle-mediated transport endoplasmic reticulum to Golgi vesicle-mediated transport Golgi organization protein complex oligomerization regulation of protein complex stability Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 60684 320714 Ensembl ENSG00000168538 ENSMUSG00000038102 UniProt Q7Z392 B2RXC1 RefSeq (mRNA) NM_021942 NM_199053 NM_177240 RefSeq (protein) NP_068761 NP_951008 NP_796214 Location (UCSC) Chr 4: 183.66 – 183.71 Mb Chr 8: 47.94 – 47.99 Mb PubMed search [3] [4]
Wikidata
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Function

The protein encoded by this gene is a subunit of the TRAPP (transport protein particle) tethering complex, which functions in intracellular vesicle trafficking. This subunit is involved in early stage endoplasmic reticulum-to-Golgi vesicle transport. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2013].