TRIM50

Tripartite motif-containing 50, also known as TRIM50, is a human gene.^[1] TRIM50 encodes an E3 ubiquitin ligase.^[2] The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The gene is located at 7q11.23, near two homologous genes, TRIM73 and TRIM74. TRIM50 is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23.

Tripartite motif-containing 50
Identifiers
Symbol	TRIM50
Alt. symbols	TRIM50A; FLJ32804; MGC138357; MGC138359
NCBI gene	135892
HGNC	19017
RefSeq	NM_178125
UniProt	Q86XT4
Other data
Locus	Chr. 7 q11.23
Search for Structures Swiss-model Domains InterPro