TRPV3-74a

TRPV3-74a is a drug which acts as a selective antagonist for the TRPV3 calcium channel. It has analgesic effects in animal studies against both neuropathic pain and normal pain responses.^[1][2]

TRPV3-74a

Identifiers
IUPAC name 3-[(S)-hydroxy(pyridin-2-yl)methyl]-1-methyl-3-[4-(trifluoromethyl)pyridin-2-yl]cyclobutan-1-ol
CAS Number	1432051-63-2
PubChem CID	71554840
ChemSpider	58922619
ChEMBL	ChEMBL3828340
Chemical and physical data
Formula	C17H17F3N2O2
Molar mass	338.330 g·mol−1
3D model (JSmol)	Interactive image
SMILES C[C@]1(C[C@@]([C@@H](C2=CC=CC=N2)O)(C3=CC(C(F)(F)F)=CC=N3)C1)O
InChI InChI=1S/C17H17F3N2O2/c1-15(24)9-16(10-15,14(23)12-4-2-3-6-21-12)13-8-11(5-7-22-13)17(18,19)20/h2-8,14,23-24H,9-10H2,1H3/t14-,15?,16?/m1/s1 Key:MTJXDHFAWXGXIN-QQFBHYJXSA-N