Tetraspanin 9

Tetraspanin 9 is a protein that in humans is encoded by the TSPAN9 gene. ^[5]

TSPAN9
Identifiers
Aliases	TSPAN9, NET-5, NET5, PP1057, tetraspanin 9
External IDs	OMIM: 613137; MGI: 1924558; HomoloGene: 4860; GeneCards: TSPAN9; OMA:TSPAN9 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12p13.33-p13.32 Start 3,077,355 bp[1] End 3,286,564 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 F3 Start 127,938,359 bp[2] End 128,120,557 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in apex of heart cerebellar hemisphere right hemisphere of cerebellum right auricle of heart left ventricle right lung right lobe of liver stromal cell of endometrium vena cava gallbladder Top expressed in gastrula yolk sac cerebellar cortex endothelial cell of lymphatic vessel decidua internal carotid artery lip right lung iris external carotid artery More reference expression data BioGPS n/a
Gene ontology Molecular function molecular function Cellular component integral component of membrane plasma membrane tetraspanin-enriched microdomain integral component of plasma membrane membrane focal adhesion Biological process cell surface receptor signaling pathway biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10867 109246 Ensembl ENSG00000011105 ENSMUSG00000030352 UniProt O75954 Q8BJU2 RefSeq (mRNA) NM_001168320 NM_006675 NM_175414 NM_001356301 NM_001379133 NM_001379134 NM_001379135 NM_001379136 RefSeq (protein) NP_001161792 NP_006666 NP_780623 NP_001343230 NP_001366062 NP_001366063 NP_001366064 NP_001366065 Location (UCSC) Chr 12: 3.08 – 3.29 Mb Chr 6: 127.94 – 128.12 Mb PubMed search [3] [4]
Wikidata
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Function

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Nov 2009].