Tagatose-bisphosphate aldolase

The enzyme tagatose-bisphosphate aldolase (EC 4.1.2.40) catalyzes the chemical reaction

D-tagatose 1,6-bisphosphate ${\displaystyle \rightleftharpoons }$ glycerone phosphate^[1] + Dglyceraldehyde 3-phosphate

tagatose-bisphosphate aldolase
Identifiers
EC no.	4.1.2.40
CAS no.	39433-95-9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is D-tagatose 1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming). This enzyme is also called D-tagatose-1,6-bisphosphate triosephosphate lyase. This enzyme participates in galactose metabolism.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1GVF.