| Year | Speaker | Lecture Title |
| 1919 | Dr Alfred North Whitehead | The Concept of Nature |
| 1923 | Dr C. D. Broad | The border-line between physics and psychology |
| 1926 | Hon. Bertrand Russell | The analysis of matter |
| 1929 | Professor G.E. Moore | Knowledge direct and indirect[2] |
| 1931 | Revd F. R. Tennant | The relations between the different departments of knowledge |
| 1935 | Mr A.D. Ritchie | The natural history of mind |
| 1938 | Sir Arthur Eddington | The philosophy of physical science |
| 1941 | Dr Cecil Alec Mace | Causality and mind |
| 1946 | Professor R. B. Braithwaite | Laws of nature, probability, and scientific explanation |
| 1947 | Sir Edmund Whittaker | The concepts of physics |
| 1949 | Professor Joseph Henry Woodger | Biology and language |
| 1953 | Professor Gilbert Ryle | Cross purposes between theories |
| 1956 | Professor Erwin Schrödinger (read by Professor J. Wisdom)[3] | The physical basis of consciousness |
| 1960 | Professor Carl Pantin | The A sciences and the B sciences |
| 1962 | Mr H.A.C. Dobbs | The concept of time |
| 1965 | Professor Hermann Bondi | Assumption and myth in physical theory |
| 1967 | Professor Georg Henrik von Wright | Time, Change and Contradiction |
| 1970 | Dr Gerd Buchdahl | Science and rational structures[4] |
| 1975 | Professor William Kneale | Grammar, logic, and arithmetic |
| 1978 | Professor Max Black[5] | Models of rationality |
| 1982 | Professor E. O. Wilson | Socio-biology and comparative social theory |
| 1985 | Professor Freeman Dyson | Origins of life |
| 1988 | Sir Andrew Huxley | Matter, life, evolution |
| 1991 | Professor Ian Hacking | Kinds of people and kinds of things |
| 1994 | Professor Michael Redhead | From physics to metaphysics |
| 1996 | Professor Martin J. S. Rudwick | Constructing geohistory in the age of revolution |
| 2000 | Professor Simon Conway Morris | Footsteps to eternity: the implications of evolution |
| 2006 | Professor Peter Galison | Images, Objects, and the Scientific Self |
| 2010 | Professor Simon Schaffer | When the stars threw down their spears: Histories of Astronomy and Empire |
| 2012 | Professor Sir Geoffrey Lloyd | The ideals of inquiry: an ancient history |
| 2019 | Professor Elliott Sober | Solving Problems in the Philosophy of Science by using (some simple ideas about) Probability |