Tasosartan

Tasosartan is an angiotensin II receptor antagonist.

Tasosartan

Clinical data
Pregnancy category	N/A
ATC code	C09CA05 (WHO)
Legal status
Legal status	Withdrawn
Identifiers
IUPAC name 2,4-dimethyl-8-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one
CAS Number	145733-36-4 Y
PubChem CID	60919
IUPHAR/BPS	6898
DrugBank	DB01349 Y
ChemSpider	54890 N
UNII	48G92V856H
CompTox Dashboard (EPA)	DTXSID40163148
Chemical and physical data
Formula	C23H21N7O
Molar mass	411.469 g·mol−1
NY (what is this?)  (verify)

It was withdrawn from FDA review by the manufacturer after phase III clinical trials showed elevated transaminases (a sign of possible liver toxicity) in a significant number of participants given the drug.^[1][2]