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Taxadiene synthase

From Wikipedia, the free encyclopedia

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The enzyme taxadiene synthase (EC 4.2.3.17) catalyzes the chemical reaction

geranylgeranyl diphosphate taxa-4,11-diene + diphosphate

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxa-4,11-diene-forming). Other names in common use include geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, and taxadiene-forming). This enzyme participates in diterpenoid biosynthesis.

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