Taxoid 14beta-hydroxylase

Taxoid 14beta-hydroxylase (EC 1.14.13.146) is an enzyme with systematic name 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl-acetate,NADPH:oxygen 14-oxidoreductase.^[1] This enzyme catalyses the following chemical reaction

10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + O₂ + NADPH + H⁺ ${\displaystyle \rightleftharpoons }$ 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP⁺ + H₂O

Taxoid 14beta-hydroxylase
Identifiers
EC no.	1.14.13.146
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Taxoid 14beta-hydroxylase requires cytochrome P450.