Temocapril

Temocapril (also known as temocaprilum [Latin]; brand name Acecol) is an ACE inhibitor. It was not approved for use in the US.

Temocapril

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	C09AA14 (WHO)
Identifiers
IUPAC name 2-[(2S)-6-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-5-oxo-2-thiophen-2-yl-1,4-thiazepan-4-yl]acetic acid
CAS Number	111902-57-9
PubChem CID	71323
ChemSpider	64431
UNII	18IZ008EU6
KEGG	D08566 Y
ChEMBL	ChEMBL2110627
CompTox Dashboard (EPA)	DTXSID3048239
Chemical and physical data
Formula	C23H28N2O5S2
Molar mass	476.61 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCOC(=O)[C@H](CCc1ccccc1)NC2CS[C@@H](CN(C2=O)CC(=O)O)c3cccs3
InChI InChI=1S/C23H28N2O5S2/c1-2-30-23(29)17(11-10-16-7-4-3-5-8-16)24-18-15-32-20(19-9-6-12-31-19)13-25(22(18)28)14-21(26)27/h3-9,12,17-18,20,24H,2,10-11,13-15H2,1H3,(H,26,27)/t17-,18?,20-/m0/s1 Key:FIQOFIRCTOWDOW-DXCJPMOASA-N
(verify)

It is administered as inactive prodrug, then converted to its active metabolite, temocaprilat.^[1]

It was patented in 1984 and approved for medical use in 1994.^[2]