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Thottapalayam virus
Species of virus From Wikipedia, the free encyclopedia
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Thottapalayam virus (TMPV) is single-stranded, enveloped, negative-sense RNA virus species of the genus Thottimvirus in the Hantaviridae family.[2] It was the first hantavirus to be isolated from a shrew.[3] It was discovered in India in 1964.[4][5]
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Natural reservoir
TPMV was first isolated from an Asian house shrew (Suncus murinus) in India in 1964. It is part of a group of hantaviruses which are hosted by shrews instead of rodents.[6] These shrew-borne thottimviruses are not known to cause any known disease in humans, unlike the similar and related orthohantaviruses, including Andes virus and Hantaan virus.[3]
TPMV was first isolated in Asian house shrews in Wenzhou of Zhejiang province, China.[7]
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Virology
Phylogenetic analysis has shown that Thottapalayam virus, and its closely related strains, is unique and forms a distinct lineage, unrelated to other hantaviruses. The closest hantavirus to TMPV is Imjin virus which demonstrates corresponding nucleotide sequences to TPMV as does Tanganya virus.[7]
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