Timiperone

Timiperone, sold under the brand name Tolopelon, is a typical antipsychotic of the butyrophenone class which is marketed in Japan for the treatment of schizophrenia.^[1][2][3][4] It is similar in chemical structure to benperidol, but has a thiourea group instead of a urea group. It acts as an antagonist for the D₂ and 5-HT_2A receptors.^[4]

Timiperone

Clinical data
Trade names	Tolopelon
AHFS/Drugs.com	International Drug Names
Routes of administration	By mouth
ATC code	none
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 1-(4-fluorophenyl)-4-[4-(2-sulfanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]butan-1-one
CAS Number	57648-21-2 Y
PubChem CID	3033151
ChemSpider	2297930 N
UNII	626DQ7N19L
KEGG	D02035 Y
ChEMBL	ChEMBL2107117
CompTox Dashboard (EPA)	DTXSID9023673
ECHA InfoCard	100.055.328
Chemical and physical data
Formula	C22H24FN3OS
Molar mass	397.51 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CN(CCC1N2C3=CC=CC=C3NC2=S)CCCC(=O)C4=CC=C(C=C4)F
InChI InChI=1S/C22H24FN3OS/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-10,18H,3,6,11-15H2,(H,24,28) N Key:YDLQKLWVKKFPII-UHFFFAOYSA-N N
NY (what is this?)  (verify)