Tombusvirus internal replication element (IRE)

In virology, the tombusvirus internal replication element (IRE) is a segment of RNA located within the region coding for p92 polymerase. This element is essential for viral replication; specifically, it is thought to be required at an early stage of replication, such as template recruitment and/or replicase complex assembly.^[1]

Tombusvirus internal replication element (IRE)
Predicted secondary structure and sequence conservation of Tombus_IRE
Identifiers
Symbol	Tombus_IRE
Rfam	RF00510
Other data
RNA type	Cis-reg
Domain(s)	Viruses
SO	SO:0000233
PDB structures	PDBe

Other non-coding RNA structures in Tombusvirus include the 3' UTR region IV^[2] and 5' UTR.^[3][4]