Trans-o-hydroxybenzylidenepyruvate hydratase-aldolase

trans-o-Hydroxybenzylidenepyruvate hydratase-aldolase (EC 4.1.2.45, 2′-hydroxybenzalpyruvate aldolase, NsaE, tHBPA hydratase-aldolase) is an enzyme with systematic name (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate hydro-lyase.^[1][2][3][4] This enzyme catalyses the following chemical reaction

(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H₂O ${\displaystyle \rightleftharpoons }$ salicylaldehyde + pyruvate

trans-o-Hydroxybenzylidenepyruvate hydratase-aldolase
Identifiers
EC no.	4.1.2.45
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This enzyme is involved in naphthalene degradation.