Triamcinolone benetonide

Triamcinolone benetonide (brand names Alcorten, Benecorten, Tibicorten; also known as triamcinolone acetonide 21-(benzoyl-β-aminoisobutyrate) or TBI) is a synthetic glucocorticoid corticosteroid.^[1][2][3]

Triamcinolone benetonide

Clinical data
Trade names	Alcorten, Benecorten, Tibicorten
Other names	Triamcinolone acetonide benzoyl-β-aminoisobutyrate; TBI; 9-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone 21-ester with N-benzoyl-2-methyl-β-alanine
Drug class	Corticosteroid; Glucocorticoid
Identifiers
IUPAC name 2-[(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-Fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]-2-oxoethyl 3-(benzoylamino)-2-methylpropanoate
CAS Number	31002-79-6
PubChem CID	62963
ChemSpider	56674
UNII	9DXL8A82MI
ChEBI	CHEBI:135852
ChEMBL	ChEMBL2105798
CompTox Dashboard (EPA)	DTXSID601026586
ECHA InfoCard	100.045.829
Chemical and physical data
Formula	C35H42FNO8
Molar mass	623.718 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC(CNC(=O)C1=CC=CC=C1)C(=O)OCC(=O)[C@@]23[C@@H](C[C@@H]4[C@@]2(C[C@@H]([C@]5([C@H]4CCC6=CC(=O)C=C[C@@]65C)F)O)C)OC(O3)(C)C
InChI InChI=1S/C35H42FNO8/c1-20(18-37-29(41)21-9-7-6-8-10-21)30(42)43-19-27(40)35-28(44-31(2,3)45-35)16-25-24-12-11-22-15-23(38)13-14-32(22,4)34(24,36)26(39)17-33(25,35)5/h6-10,13-15,20,24-26,28,39H,11-12,16-19H2,1-5H3,(H,37,41)/t20?,24-,25-,26-,28+,32-,33-,34-,35+/m0/s1 Key:GUYPYYARYIIWJZ-CYEPYHPTSA-N