Trichomonasvirus

Trichomonasvirus is a genus of viruses, in the family Pseudototiviridae. The protozoan parasite Trichomonas vaginalis serves as the natural host. There are five species in this genus.^[1][2]

Trichomonasvirus
Cryo-EM image of protein surface of Trichomonas vaginalis virus 1
Virus classification
(unranked):	Virus
Realm:	Riboviria
Kingdom:	Orthornavirae
Phylum:	Duplornaviricota
Class:	Chrymotiviricetes
Order:	Ghabrivirales
Family:	Pseudototiviridae
Genus:	Trichomonasvirus

Taxonomy

The following four species are assigned to the genus:^[2]

• Trichomonasvirus vagiprimus
• Trichomonasvirus vagiquartus
• Trichomonasvirus vagiquintus
• Trichomonasvirus vagisecundus
• Trichomonasvirus vagitertius

Structure

Viruses in Trichomonasvirus are non-enveloped, with icosahedral geometries, and T=2 symmetry. The diameter is around 36 nm. Genomes are linear and non-segmented, around 4.6-4.9kb in length. The genome has 2 open reading frames.^[1]

Genus	Structure	Symmetry	Capsid	Genomic arrangement	Genomic segmentation
Trichomonasvirus	Icosahedral	T=2	Non-enveloped	Linear

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment to host receptors, which mediates endocytosis. Replication follows the double-stranded RNA virus replication model. Double-stranded RNA virus transcription is the method of transcription. Protozoan parasite Trichomonas vaginalis serve as the natural host.^[1]

Genus	Host details	Tissue tropism	Entry details	Release details	Replication site	Assembly site	Transmission
Trichomonasvirus	Protozoa	Endocytosis	Unknown	Unknown	Cytoplasm	Cytoplasm	Unknown