Trimerelysin II

Trimerelysin II (EC 3.4.24.53, Trimeresurus metalloendopeptidase II, proteinase H2, H2-proteinase) is an enzyme.^[1][2] This enzyme catalyses the following chemical reaction

Cleavage of Asn³-Gln, His¹⁰-Leu and Ala¹⁴-Leu in the insulin B chain, and the bond Z-Gly-Pro-Leu-Gly-Pro in a small molecule substrate of microbial collagenase

Trimerelysin II
Identifiers
EC no.	3.4.24.53
CAS no.	151125-15-4
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This endopeptidase is present in the venom of the habu snake (Trimeresurus flavoviridis).