Top Qs
Timeline
Chat
Perspective
Trimetrexate
Chemical compound From Wikipedia, the free encyclopedia
Remove ads
Trimetrexate is a quinazoline derivative. It is a dihydrofolate reductase inhibitor.[1]
Remove ads
Uses
It has been used with leucovorin in treating pneumocystis pneumonia.[2]
It has been investigated for use in treating leiomyosarcoma.[3] It is a methotrexate (MTX) analog that is active against transport-deficient MTX-resistant tumor cells that overcome the acquired and natural resistance to methotrexate. Other uses include skin lymphoma. [4]
References
External links
Wikiwand - on
Seamless Wikipedia browsing. On steroids.
Remove ads