Tropine acyltransferase

Tropine acyltransferase (EC 2.3.1.185, tropine:acyl-CoA transferase, acetyl-CoA:tropan-3-ol acyltransferase, tropine acetyltransferase, tropine tigloyltransferase, TAT) is an enzyme with systematic name acyl-CoA:tropine O-acyltransferase.^[1][2][3][4] This enzyme catalyses the following chemical reaction

acyl-CoA + tropine ${\displaystyle \rightleftharpoons }$ CoA + O-acyltropine

Tropine acyltransferase
Identifiers
EC no.	2.3.1.185
CAS no.	162535-29-7&title= 138440-79-6, 162535-29-7
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This enzyme exhibits absolute specificity for the endo/3alpha configuration found in tropine as pseudotropine.