UDP-2,3-diacylglucosamine diphosphatase

UDP-2,3-diacylglucosamine diphosphatase (EC 3.6.1.54, UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine pyrophosphatase, ybbF (gene), lpxH (gene)) is an enzyme with systematic name UDP-2,3-bis((3R)-3-hydroxymyristoyl)-alpha-D-glucosamine 2,3-bis((3R)-3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate phosphohydrolase.^[1][2] This enzyme catalyses the following chemical reaction

UDP-2,3-bis[(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine + H₂O ${\displaystyle \rightleftharpoons }$ 2,3-bis[(3R)-3-hydroxymyristoyl]-beta-D-glucosaminyl 1-phosphate + UMP

UDP-2,3-diacylglucosamine diphosphatase
Identifiers
EC no.	3.6.1.54
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

The enzyme catalyses a step in the biosynthesis of lipid A.