UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting)

UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115, FlaA1, UDP-N-acetylglucosamine 5-inverting 4,6-dehydratase, PseB, UDP-N-acetylglucosamine hydro-lyase (inverting, UDP-2-acetamido-2,6-dideoxy-β-L)arabino-hex-4-ulose-forming)) is an enzyme with systematic name UDP-N-acetyl-α-D-glucosamine hydro-lyase (inverting; UDP-2-acetamido-2,6-dideoxy-β-L-arabino-hex-4-ulose-forming).^[1][2][3] This enzyme catalyses the following chemical reaction

UDP-N-acetyl-α-D-glucosamine ${\displaystyle \rightleftharpoons }$ UDP-2-acetamido-2,6-dideoxy-β-L-arabino-hex-4-ulose + H₂O

UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting)
Identifiers
EC no.	4.2.1.115
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This enzyme contains NADP⁺ as a cofactor.