UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining)

UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135, PglF) is an enzyme with systematic name UDP-N-acetyl-α-Dglucosamine hydro-lyase (configuration-retaining; UDP-2-acetamido-2,6-dideoxy-α-Dxylo-hex-4-ulose-forming).^[1][2] This enzyme catalyses the following chemical reaction

UDP-N-acetyl-α-D-glucosamine ${\displaystyle \rightleftharpoons }$ UDP-2-acetamido-2,6-dideoxy-α-D-xylo-hex-4-ulose + H₂O

UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining)
Identifiers
EC no.	4.2.1.135
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
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This enzyme contains NAD⁺ as a cofactor.