UGT1A

UDP glucuronosyltransferase 1 family, polypeptide A cluster (UGT1A) is a human gene locus that includes several UDP glucuronosyltransferases.^[2]

UGT1A
Identifiers
Aliases	UGT1A, GNT1, UGT, UGT1, UGT1A@, UDP glucuronosyltransferase family 1 member A complex locus
External IDs	GeneCards: UGT1A; OMA:UGT1A - orthologs
Orthologs Species Human Mouse Entrez 7361 n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search [1] n/a
Wikidata
View/Edit Human

The UGT1A locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its promoter.^[2]