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Ulp1 peptidase

Class of enzymes From Wikipedia, the free encyclopedia

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Ulp1 peptidase (EC 3.4.22.68, Smt3-protein conjugate proteinase, Ubl-specific protease 1, Ulp1, Ulp1 endopeptidase, Ulp1 protease) is an enzyme.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction

Hydrolysis of the alpha-linked peptide bond in the sequence Gly-Gly-!Ala-Thr-Tyr at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptide, Smt3

The enzyme from Saccharomyces cerevisiae can also recognize small ubiquitin-like modifier 1 (SUMO-1) from human.

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