VIS1

VIS1 (viral integration site 1), also known as HIS-1, is a long non-coding RNA. It was originally identified in mice in a screen for genes involved in the development of myeloid leukemia. In murine myeloid leukemias, this gene is a common site of viral insertion by the murine ecotropic retrovirus CasBrM^[2][3] It is conserved amongst vertebrates, including human, mice, cats, pigs, cattle and dogs.^[4] Expression of VIS1 is restricted to epithelial cells, leukemias and carcinomas.^[5]

VIS1
Identifiers
Aliases	VIS1, HIS-1, HIS1, viral integration site 1
External IDs	OMIM: 164755; GeneCards: VIS1; OMA:VIS1 - orthologs
Orthologs Species Human Mouse Entrez 7435 n/a Ensembl ENSG00000276706 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search [1] n/a
Wikidata
View/Edit Human

See also

• Long noncoding RNA