VLX1570

VLX1570 is a drug used in scientific research which acts as a non selective inhibitor of proteasome deubiquitinases. It has potential applications in the treatment of cancer, though was discontinued in clinical trials due to excessive toxicity.^[1][2][3][4]

VLX1570

Identifiers
IUPAC name (3E,5E)-3,5-bis[(4-fluoro-3-nitrophenyl)methylidene]-1-prop-2-enoylazepan-4-one
CAS Number	1956378-23-6
PubChem CID	71523377
Chemical and physical data
Formula	C23H17F2N3O6
Molar mass	469.401 g·mol−1
3D model (JSmol)	Interactive image
SMILES C=CC(=O)N1CC/C(=C\C2=CC(=C(C=C2)F)[N+](=O)[O-])/C(=O)/C(=C/C3=CC(=C(C=C3)F)[N+](=O)[O-])/C1
InChI InChI=1S/C23H17F2N3O6/c1-2-22(29)26-8-7-16(9-14-3-5-18(24)20(11-14)27(31)32)23(30)17(13-26)10-15-4-6-19(25)21(12-15)28(33)34/h2-6,9-12H,1,7-8,13H2/b16-9+,17-10+ Key:SCKXBVLYWLLALY-CZCYGEDCSA-N