VUAA1

VUAA1 is a chemical compound that works by over activating an insect's olfactory senses causing a repellent effect. It is considered to be an Orco allosteric agonist.^[1] It was discovered at Vanderbilt University^[2] with research being partially funded by the Bill and Melinda Gates Foundation.^[3]

VUAA1

Names
Preferred IUPAC name N-(4-Ethylphenyl)-2-{[4-ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
Identifiers
CAS Number	525582-84-7 Y
3D model (JSmol)	Interactive image
ChemSpider	1105882 Y
PubChem CID	1319135
UNII	ZZ52US95LQ Y
CompTox Dashboard (EPA)	DTXSID401029734
InChI InChI=1S/C19H21N5OS/c1-3-14-7-9-16(10-8-14)21-17(25)13-26-19-23-22-18(24(19)4-2)15-6-5-11-20-12-15/h5-12H,3-4,13H2,1-2H3,(H,21,25) Y Key: UWCCKVJVOHTHAF-UHFFFAOYSA-N Y
SMILES CCN1C(C2=CN=CC=C2)=NN=C1SCC(NC3=CC=C(CC)C=C3)=O
Properties
Chemical formula	C19H21N5OS
Molar mass	367.47 g·mol−1
Hazards
GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H315, H319, H335
Precautionary statements	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references

VUAA1 is an agonist believed to work by overloading an insect's odorant receptors. It may be 1000 times stronger than DEET^[4] and may lead to, "a powerful new family of compounds that can be used to disrupt the destructive behaviors of nuisance insects, agricultural pests, and disease vectors alike."^[5]

VUAA1 has also been shown to stimulate mosquito sperm motility, thus showing a link between a mosquito's sense of smell and reproduction.^[6]