Vts1

Vts1 is a post-transcriptional regulator that has RNA-binding Sterile alpha motif (SAM) domain.^[2][3] The protein is found in Saccharomyces cerevisiae and several eukaryotes. In Saccharomyces the Vts1 impacts vesicular transport and sporulation.^[4][5]

Vts1
Crystal structure of Vts1p–SRE complex.[1]
Identifiers
Symbol	Vts1
Pfam	PF07647
SCOP2	1b0x / SCOPe / SUPFAM
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

Interactions

Secondary structure motif of RNA region interacting with Vts1

Protein-protein interactions through SAM domains participate in different regulatory activities such as signal transduction. Proteins having such domains were also shown to recognize and interact with RNA structures of similar shape to the Smaug response element (SRE).^[6] Vts1 binds to RNA targets that have CUGGC on hairpin loops.^[7]