X8 protein domain

In molecular biology, the X8 domain, is thought to play a role in targeting the plasmodesmata by providing it with structural support. The domain is able to do this since it contains signal sequences for a glycosylphosphatidylinositol (GPI) linkage to the extracellular face of the plasma membrane. This domain is involved in carbohydrate binding.^[1]

X8
Identifiers
Symbol	X8
Pfam	PF07983
InterPro	IPR012946
SCOP2	1occ / SCOPe / SUPFAM
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

Structure

The X8 domain^[2] contains 6 conserved cysteine residues that presumably form three disulphide bridges. The domain is also found in an Olive pollen allergen^[3] as well as at the C terminus of family 17 glycosyl hydrolases.^[4]