YEATS domain

In molecular biology, the YEATS domain is a protein domain found in a variety of proteins from eukaryotic organisms.^[1] YEATS domain proteins are found in a variety of chromatin modification molecular complexes. Structurally the domain has an immunoglobulin like fold.^[2] The YEATS domain has shown to bind to acetyllysine protein modifications.^[3] In addition to lysine acetylation, the YEATS domain has shown to be a reader domain for various lysine acylations, with highest affinity for lysine crotonylation.^{[4] [5]}

YEATS domain
Identifiers
Symbol	YEATS
Pfam	PF03366
InterPro	IPR005033
PROSITE	PS51037
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary PDB 4tmp​, 3fk3​, 3rls​, 2l7e​, 3qrl​

See also

Bromodomain